Perinatal adverse eventsDistribution of risk factors at 5 years. Numbers refer to the different criteria on the right. Twenty percent had multiple (Mtpl) concomitant risk factors.
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Inclusion criteria1) Birth weight 2000 g or less
2) Apgar <7 at 5 or 15 min 3) Hyperbilirubinemia: at least two serum bilirubin values of 340 µmol/l (20 mg/100ml) or more, or a need for blood exchange transfusion 4) Hypoglycemia: at least two blood glucose values of 1.67 mmol/l (30 mg/100ml) or less for full term babies and 1.21 mmol/l (22 mg/100ml) or less for preterm babies (less than 37 gestational weeks) 5) Diabetic mother 6) Neurological symptoms: marked hypotonia, apathy, hyperexcitability, rigidity, convulsions, apnea 7) Need for external ventilation 8) Septic infection, bacteriologically verified |